Carnitine, derived from an amino acid, is found in nearly all cells of the body. Its name is derived from Latin carnus or flesh, as the compound was isolated from meat. Animal products like meat, fish, poultry and milk are the best sources. In general, the redder the meat, the higher its Carnitine content. Carnitine occurs in two forms, known as D and L, which are mirror images of each other. Only L-Carnitine is active in the body and the form found in food. A well-balanced, non-vegetarian Western diet is estimated to provide 100 – 300 mg of L-Carnitine per day. However, biosynthesis of L-Carnitine accounts only for 25% of the daily needs. Thus, supplementation either in the diet or as a nutritional supplement is required.
L-Carnitine plays an important role in energy production. It transports long-chain fatty acids into the mitochondria so they can be oxidized to produce energy. It also removes toxic compounds from mitochondria to prevent accumulation. Additionally, a sufficiently high concentration of free L-carnitine inside the mitochondria can maintain energy generating processes that depend on the availability of free coenzyme A. However, if there is only little free coenzyme A available, L-Carnitine can bind the acetyl-units temporarily and ensure sufficient energy is generated.
As L-Carnitine is mainly accumulated in muscle and heart, with its role in energy metabolism, it is proposed to play crucial roles in diseased populations such as those with heart disease, as well as among healthy athletes where it has been shown to modulate exercise capacity and recovery.
Bio-A Nutri L-Carnitine
Powerlife Bio-A Nutri L-Carnitine features L-Carnitine L-Tartrate that facilitate better absorption of L-Carnitine in the body than common L-Carnitine, providing the most effective and stable form of L-Carnitine for heart health and muscle recovery. Besides that, Powerlife Bio-A Nutri L-Carnitine contains the optimal dose of L-Carnitine for body’s requirement.
Powerlife Bio-A Nutri L-Carnitine works best together with Powerlife Bio-A Nutri Ubiquinol. It was reported that the duo exerts cardioprotective effects as well as improving quality of life (QoL) for patients with heart disease. Powerlife Bio-A Nutri L-Carnitine plays an important role in energy production in the myocardium and inhibits fatty acid ester reposition that occurs during ischemic events. Whilst Powerlife Bio-A Nutri Ubiquinol plays a role in energy production process in the mitochondria and works as an antioxidant too. Besides that, study has reported the beneficial effects of L-Carnitine and Ubiquinol in improving migraine symptoms and reduce serum levels of lactate after 8 weeks*. Supplementing both Powerlife Bio-A Nutri L-Carnitine and Powerlife Bio-A Nutri Ubiquinol could modulate energy metabolism and improve post-exercise muscle recovery in athletes. Furthermore, the duo could improve sperm health, protecting the sperm from the negative effects of reactive oxygen species as well as sperm maturation.
MACNEW HEART DISEASE HEALTH RELATED QUALITY OF LIFE MEASUREMENT
Sharifi et al. J Cardiovasc Thorac Res, 2017. Supplementation of 150mg/day CoQ10 and 1200 mg/day L-Carnitine improved quality of life for Myocardial Infarction patients.
CoQ10 + L-Carnitine
MAC GLOBAL SCORE
HEADACHE DIARY RESULTS:
DURATION OF HEADACHE X FREQUENCY OF HEADACHE
CoQ10 + L-Carnitine
(hours x no. of attacks)
Hajishemi et al. Cephalalgia, 2019. Supplementation of 30 mg/day of CoQ10 and 500 mg/day L-Carnitine for 8 weeks provide positive effects on migraine headache.
Support heart health
Improve quality of life for patients with heart disease
Reduce migraine symptoms, frequency, and pain
Enhance muscles recovery after exercise
Improve men’s reproductive health
L-Carnitine (as L-Carnitine Tartrate) 600 mg
Adults: Take 1 caplet each time, twice daily after meals